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KMID : 0357919780120020187
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Korean Journal of Pathology
1978 Volume.12 No. 2 p.187 ~ p.192
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A Case of Paroxysmal Nocturnal Hemoglobinuria
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배창연(裵昌煉)/C.H. Bae
김경선(金京善)/신경호(申敬)/김재식(金在植)/김중명(金重明)/K.H. Shin/K.S. Kim/J.S. Kim/J.M. Kim
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Abstract
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Clinical and laboratory observation were made in a case of paroxysmal nocturnal
hemoglobinuria(PNH). The patient was 20-years old male college student, who was
admitted with chief complaint of general weakness with dyspnea on exertion and dark
brown urine.
The peripheral blood revealed severe anemia with reticulocytosis, moderate increased
bilirubin, positive Ham's test and positive on sucrose hemolysis test. Marked homogl-
obinuria and hemosiderinuria on urinalysis and the bone marrow aspiration showed
normocellular with markedly erythroid hyperplasia.
The findings of chest X-ray and ECG were in normal limits.
He was treated with packed cell transfusion and dischared with clinical improvement
of hemoglobinuria.
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KEYWORD
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